Activity record

PGDB_A029275

Assay: % DegradationTarget: PTPN1QC: standardized
Activity overview

DC50 = 7.56 nM

TargetPTPN1
Cell lineHCT116
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001836
PatentWO2026119184
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C028710
Compound IDPGDB_C028710
Compound154
Source record IDPGDB_C028710
InChIKeyVOWSTJQQUXNRCD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001836
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetPTPN1
E3Not specified
Cell lineHCT116
OrganismHomo sapiens

Source evidence

Patent IDWO2026119184
Activity table
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