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Compound
PGDB_C028710
5 activity records1 related patents
2D structure
Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(-c3ccc(-c4nc(-c5cc(OCC6CC6(F)F)c6sc(C(F)(F)P(=O)(O)F)c(Br)c6c5)n[nH]4)cc3)cc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 98.5 | % | - | - | - | - | HCT116 | WO2026119184 | PGDB_A007754 | PGDB_C028710 | PGDB_AS000959 | View |
| DC50 | - | = | 2.23 | nM | - | — | - | - | HCT116 | WO2026119184 | PGDB_A022239 | PGDB_C028710 | PGDB_AS000045 | View |
| DC50 | - | = | 7.56 | nM | - | — | PTPN1 | - | HCT116 | WO2026119184 | PGDB_A029275 | PGDB_C028710 | PGDB_AS001836 | View |
| Selectivity index | N2/1B | = | 3.39 | fold | - | — | - | - | HCT116 | WO2026119184 | PGDB_A030491 | PGDB_C028710 | PGDB_AS000119 | View |
| Dmax | - | = | 99.2 | % | - | - | - | - | HCT116 | WO2026119184 | PGDB_A066491 | PGDB_C028710 | PGDB_AS000736 | View |