Activity record

PGDB_A029351

Assay: % DegradationTarget: PTPN1QC: standardized
Activity overview

DC50 = 37.29 nM

TargetPTPN1
Cell lineHCT116
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001836
PatentWO2026119184
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C028714
Compound IDPGDB_C028714
Compound165
Source record IDPGDB_C028714
InChIKeyZPRIZXGDZIMCDL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001836
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetPTPN1
E3Not specified
Cell lineHCT116
OrganismHomo sapiens

Source evidence

Patent IDWO2026119184
Activity table
Page 189 · table single