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Compound
PGDB_C028714
5 activity records1 related patents
2D structure
C=C(C)C#Cc1cc(-c2nnc(-c3cc(C)n(-c4ccc5c(C6CCC(=O)NC6=O)nn(C)c5c4)c3C)[nH]2)cc2c(Br)c(C(F)(F)P(=O)(O)O)sc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 10.34 | nM | - | — | - | - | HCT116 | WO2026119184 | PGDB_A009773 | PGDB_C028714 | PGDB_AS000045 | View |
| Selectivity index | N2/1B | = | 3.61 | fold | - | — | - | - | HCT116 | WO2026119184 | PGDB_A016060 | PGDB_C028714 | PGDB_AS000119 | View |
| Dmax | - | = | 95.8 | % | - | - | - | - | HCT116 | WO2026119184 | PGDB_A022575 | PGDB_C028714 | PGDB_AS000959 | View |
| DC50 | - | = | 37.29 | nM | - | — | PTPN1 | - | HCT116 | WO2026119184 | PGDB_A029351 | PGDB_C028714 | PGDB_AS001836 | View |
| Dmax | - | = | 99.7 | % | - | - | - | - | HCT116 | WO2026119184 | PGDB_A064837 | PGDB_C028714 | PGDB_AS000736 | View |