Activity record

PGDB_A029496

Assay: % DegradationQC: ambiguous
Activity overview

DC50 = 12 nM

Cell lineMM.1S
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001567
PatentWO2022219412A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001782
Compound IDPGDB_C001782
Compound35
Source record IDPGDB_C001782
InChIKeyYDQJAXLKJIPHKM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001567
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TargetIKZF1 | IKZF3
E3Not specified
Cell lineMM.1S

Source evidence

Patent IDWO2022219412A1
Compound location

35

35 enlarged structure35 location on patent page 112
Activity table
Page 171 · table single