Assay

PGDB_AS001567

System: cell_basedTarget: IKZF1 | IKZF3Cell line: MM.1S
Assay context summary

Assay context

14 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF1 | IKZF3
E3Not specified
Cell lineMM.1S
Activity compounds and values

Activity records

14 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001760
DC50-=27nM-—--MM.1SWO2022219412A1PGDB_A009421PGDB_C001760PGDB_AS001567View
2D structure for PGDB_C001763
DC50-=22nM-—--MM.1SWO2022219412A1PGDB_A009589PGDB_C001763PGDB_AS001567View
2D structure for PGDB_C001779
DC50-=17nM-—--MM.1SWO2022219412A1PGDB_A014499PGDB_C001779PGDB_AS001567View
2D structure for PGDB_C001782
DC50-=12nM-—--MM.1SWO2022219412A1PGDB_A029496PGDB_C001782PGDB_AS001567View
2D structure for PGDB_C001770
DC50-=22nM-—--MM.1SWO2022219412A1PGDB_A044612PGDB_C001770PGDB_AS001567View
2D structure for PGDB_C001746
DC50-=13nM-—--MM.1SWO2022219412A1PGDB_A051049PGDB_C001746PGDB_AS001567View
2D structure for PGDB_C001728
DC50-=25nM-—--MM.1SWO2022219412A1PGDB_A052174PGDB_C001728PGDB_AS001567View
2D structure for PGDB_C001749
DC50-=26nM-—--MM.1SWO2022219412A1PGDB_A057733PGDB_C001749PGDB_AS001567View
2D structure for PGDB_C001759
DC50-=26nM-—--MM.1SWO2022219412A1PGDB_A058781PGDB_C001759PGDB_AS001567View
2D structure for PGDB_C000518
DC50-=6nM-—--MM.1SWO2022219412A1PGDB_A066413PGDB_C000518PGDB_AS001567View
2D structure for PGDB_C001769
DC50-=30nM-—--MM.1SWO2022219412A1PGDB_A069198PGDB_C001769PGDB_AS001567View
2D structure for PGDB_C001783
DC50-=6nM-—--MM.1SWO2022219412A1PGDB_A073291PGDB_C001783PGDB_AS001567View
2D structure for PGDB_C001724
DC50-=16nM-—--MM.1SWO2022219412A1PGDB_A073356PGDB_C001724PGDB_AS001567View
2D structure for PGDB_C001781
DC50-=27nM-—--MM.1SWO2022219412A1PGDB_A074800PGDB_C001781PGDB_AS001567View
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