Activity record

PGDB_A029710

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 46 %

TargetGSPT1
Cell lineHL-60
Concentration0.1 uM
Time2 h
Assay / Readout% Degradation
Assay IDPGDB_AS000569
PatentWO2024073871A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002855
Compound IDPGDB_C002855
Compound6;6;6;6
Source record IDPGDB_C002855
InChIKeyPQGCMPPUJYTHQU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000569
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration0.1 uM
Treatment time2 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2024073871A1
Compound location

6;6;6;6

6;6;6;6 enlarged structure6;6;6;6 location on patent page 29
Activity table
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