Assay

PGDB_AS000569

System: cell_basedTarget: GSPT1Cell line: HL-60
Assay context summary

Assay context

28 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetGSPT1
E3Not specified
Cell lineHL-60
Detection targetprotein_degradation
Activity compounds and values

Activity records

28 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C002859
% Degradation-=40%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A009692PGDB_C002859PGDB_AS000569View
2D structure for PGDB_C002869
% Degradation-=0%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A012950PGDB_C002869PGDB_AS000569View
2D structure for PGDB_C002852
% Degradation-=30%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A017711PGDB_C002852PGDB_AS000569View
2D structure for PGDB_C002872
% Degradation-=33%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A023723PGDB_C002872PGDB_AS000569View
2D structure for PGDB_C002850
% Degradation-=45%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A027843PGDB_C002850PGDB_AS000569View
2D structure for PGDB_C002855
% Degradation-=46%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A029710PGDB_C002855PGDB_AS000569View
2D structure for PGDB_C002865
% Degradation-=26%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A031282PGDB_C002865PGDB_AS000569View
2D structure for PGDB_C002867
% Degradation-=32%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A032535PGDB_C002867PGDB_AS000569View
2D structure for PGDB_C002851
% Degradation-=0%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A032661PGDB_C002851PGDB_AS000569View
2D structure for PGDB_C002861
% Degradation-=0%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A033477PGDB_C002861PGDB_AS000569View
2D structure for PGDB_C002858
% Degradation-=0%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A035494PGDB_C002858PGDB_AS000569View
2D structure for PGDB_C002853
% Degradation-=0%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A037039PGDB_C002853PGDB_AS000569View
2D structure for PGDB_C002871
% Degradation-=29%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A038672PGDB_C002871PGDB_AS000569View
2D structure for PGDB_C002868
% Degradation-=15%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A041698PGDB_C002868PGDB_AS000569View
2D structure for PGDB_C002875
% Degradation-=45%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A042909PGDB_C002875PGDB_AS000569View
2D structure for PGDB_C002862
% Degradation-=0%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A046051PGDB_C002862PGDB_AS000569View
2D structure for PGDB_C002857
% Degradation-=70%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A047015PGDB_C002857PGDB_AS000569View
2D structure for PGDB_C002854
% Degradation-=17%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A047878PGDB_C002854PGDB_AS000569View
2D structure for PGDB_C002870
% Degradation-=35%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A050995PGDB_C002870PGDB_AS000569View
2D structure for PGDB_C002866
% Degradation-=36%0.1 uM2 hGSPT1-HL-60WO2024073871A1PGDB_A052265PGDB_C002866PGDB_AS000569View
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