Activity record

PGDB_A030209

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 > 10000 nM

TargetGSPT1
Cell lineHEK293
Time72 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000381
PatentIL323841A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008158
Compound IDPGDB_C008158
Compound6
Source record IDPGDB_C008158
InChIKeyXCWDMXYXXAZRMR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000381
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time72 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDIL323841A
Compound location

6

6 enlarged structure6 location on patent page 44
Activity table
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