Activity record

PGDB_A030309

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 > 30 uM

TargetGSPT1
Cell lineHEK293T
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000322
PatentUS20230265071A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000469
Compound IDPGDB_C000469
Compound131;131
Source record IDPGDB_C000469
InChIKeyGLHKSXCVDBGDKA-ZURQMKNRSA-N

Assay context

Assay IDPGDB_AS000322
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetGSPT1
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDUS20230265071A1
Compound location

131;131

131;131 enlarged structure131;131 location on patent page 57
Activity table
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