Activity record

PGDB_A030658

Assay: % DegradationTarget: SALL4QC: standardized
Activity overview

DC50 = 0.0052 uM

TargetSALL4
Cell lineHT-1080
Time20 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002491
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007563
Compound IDPGDB_C007563
Compound化合物19
Source record IDPGDB_C007563
InChIKeyMUKCJOOKCZSQNW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002491
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time20 h
Detection targetprotein_degradation
TargetSALL4
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物19

化合物19 enlarged structure化合物19 location on patent page 113
Activity table
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