Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C007563
5 activity records2 related patents
2D structure
O=C1CCC(N2C(=O)c3cccc4c(Cc5ccc(CN6CCOCC6)cc5)ccc2c34)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 93.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A014758 | PGDB_C007563 | PGDB_AS002293 | View |
| GI50 | - | < | 1 | nM | - | — | - | - | NCI-H929 | EA048567B1 | PGDB_A027245 | PGDB_C007563 | PGDB_AS000655 | View |
| DC50 | - | = | 0.0052 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A030658 | PGDB_C007563 | PGDB_AS002491 | View |
| DC50 | - | = | 0.157 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A041248 | PGDB_C007563 | PGDB_AS002064 | View |
| Dmax | - | = | 64.6 | % | Concentration context: HiBiT SALL4: D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A053718 | PGDB_C007563 | PGDB_AS000801 | View |