Activity record

PGDB_A031803

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 0.09764 nM

TargetKRAS
Cell lineNCI-H358
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000944
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011603
Compound IDPGDB_C011603
CompoundExample 16
Source record IDPGDB_C011603
InChIKeyLSSANTBSBINZBL-NLNZRBICSA-N

Assay context

Assay IDPGDB_AS000944
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineNCI-H358
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Example 16

Example 16 enlarged structureExample 16 location on patent page 58
Activity table
Page 226 · table single