Assay

PGDB_AS000944

System: cell_basedCell line: NCI-H358
Assay context summary

Assay context

7 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
E3Not specified
Cell lineNCI-H358
OrganismHomo sapiens
TechnologyCCK-8
Detection target% Cell viability
Activity compounds and values

Activity records

7 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C011587
IC50-=5.017nM-—KRAS-NCI-H358WO2025214350A1PGDB_A008260PGDB_C011587PGDB_AS000944View
2D structure for PGDB_C011603
IC50-=0.09764nM-—KRAS-NCI-H358WO2025214350A1PGDB_A031803PGDB_C011603PGDB_AS000944View
2D structure for PGDB_C011633
IC50-=0.6982nM-—KRAS-NCI-H358WO2025214350A1PGDB_A045157PGDB_C011633PGDB_AS000944View
2D structure for PGDB_C011631
IC50-=1.753nM-—KRAS-NCI-H358WO2025214350A1PGDB_A045842PGDB_C011631PGDB_AS000944View
2D structure for PGDB_C011632
IC50-=0.2651nM-—KRAS-NCI-H358WO2025214350A1PGDB_A058014PGDB_C011632PGDB_AS000944View
2D structure for PGDB_C011604
IC50-=0.06482nM-—KRAS-NCI-H358WO2025214350A1PGDB_A072759PGDB_C011604PGDB_AS000944View
2D structure for PGDB_C011605
IC50-=0.05751nM-—KRAS-NCI-H358WO2025214350A1PGDB_A074224PGDB_C011605PGDB_AS000944View
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