Activity record

PGDB_A032363

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 196 nM

TargetGSPT1
Cell lineHL-60
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000219
PatentWO2024073871A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002857
Compound IDPGDB_C002857
Compound8;8;8;8
Source record IDPGDB_C002857
InChIKeyWSNDYWOVEHVMCC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000219
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2024073871A1
Compound location

8;8;8;8

8;8;8;8 enlarged structure8;8;8;8 location on patent page 29
Activity table
Page 94 · table start
Page 95 · table end