Activity record

PGDB_A032454

Assay: % DegradationTarget: CSNK1A1QC: ambiguous
Activity overview

degradation <= 25 %

TargetCSNK1A1
Cell lineNCI-H929
Concentration20 uM
Time24 h
Assay / Readout% Degradation
Assay IDPGDB_AS000343
PatentAU2020392427A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019029
Compound IDPGDB_C019029
Compound8;8
Source record IDPGDB_C019019
InChIKeyMESQJKHNKPAXCZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000343
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration20 uM
Treatment time24 h
Detection targetprotein_degradation
TargetCSNK1A1
E3Not specified
Cell lineNCI-H929
OrganismHomo sapiens

Source evidence

Patent IDAU2020392427A1
Compound location

8;8

8;8 enlarged structure8;8 location on patent page 35
Activity table
Page 114 · table single