Activity record

PGDB_A032590

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 0.5-1 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS001560
PatentWO2022187423A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009802
Compound IDPGDB_C009802
Compound221
Source record IDPGDB_C009802
InChIKeyHAWLSVPQOCLPJJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001560
Assay familybinding
Assay systembiochemical
ReadoutIC50
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2022187423A1
Compound location

221

221 enlarged structure221 location on patent page 56
Activity table
Page 191 · table start
Page 192 · table end