PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2022187423A1

AssigneeUniversity Of Michigan System

TitleCereblon ligands

Family ID80820057

Family members2

Filing year2022

Publication date2022-09-09

JurisdictionWO

Compounds60

Activity records60

Assays1

Activity compounds and values

Activity records

60 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A008926	PGDB_C009809	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A009117	PGDB_C009805	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A009699	PGDB_C009825	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A010916	PGDB_C009820	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A011670	PGDB_C009821	PGDB_AS001560	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A013774	PGDB_C009819	PGDB_AS001560	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A014280	PGDB_C009804	PGDB_AS001560	View
IC50	-	=	0.5-1	uM	-	—	CRBN	CRBN	-	PGDB_A014642	PGDB_C009849	PGDB_AS001560	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A015387	PGDB_C009827	PGDB_AS001560	View
IC50	-	=	0.5-1	uM	-	—	CRBN	CRBN	-	PGDB_A016589	PGDB_C009811	PGDB_AS001560	View
IC50	-	=	0.5-1	uM	-	—	CRBN	CRBN	-	PGDB_A017391	PGDB_C009828	PGDB_AS001560	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A019824	PGDB_C009799	PGDB_AS001560	View
IC50	-	=	0.5-1	uM	-	—	CRBN	CRBN	-	PGDB_A021474	PGDB_C009812	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A026965	PGDB_C009807	PGDB_AS001560	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A029324	PGDB_C009848	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A030134	PGDB_C009801	PGDB_AS001560	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A032086	PGDB_C009838	PGDB_AS001560	View
IC50	-	<=	0.5	uM	-	—	CRBN	CRBN	-	PGDB_A032423	PGDB_C009834	PGDB_AS001560	View
IC50	-	=	0.5-1	uM	-	—	CRBN	CRBN	-	PGDB_A032590	PGDB_C009802	PGDB_AS001560	View
IC50	-	>	10	uM	-	—	CRBN	CRBN	-	PGDB_A032719	PGDB_C009798	PGDB_AS001560	View

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