Activity record

PGDB_A032719

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 > 10 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS001560
PatentWO2022187423A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009798
Compound IDPGDB_C009798
Compound217
Source record IDPGDB_C009798
InChIKeyLSQHTKNMGQNLEF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001560
Assay familybinding
Assay systembiochemical
ReadoutIC50
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2022187423A1
Compound location

217

217 enlarged structure217 location on patent page 56
Activity table
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