Activity record

PGDB_A032736

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 > 500 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001297
PatentWO2022219412A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001731
Compound IDPGDB_C001731
Compound13
Source record IDPGDB_C001731
InChIKeyUYKHGMUGYOVGSG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001297
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219412A1
Compound location

13

13 enlarged structure13 location on patent page 110
Activity table
Page 167 · table start
Page 168 · table end