Activity record

PGDB_A033868

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

GI50 = 7.88 nM

TargetGSPT1
Cell lineNCI-H929
Time48 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS000710
PatentWO2023237116A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002261
Compound IDPGDB_C002261
CompoundExample 83
Source record IDPGDB_C002261
InChIKeyGTINEENEVGGWKC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000710
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineNCI-H929

Source evidence

Patent IDWO2023237116A1
Compound location

Example 83

Example 83 enlarged structureExample 83 location on patent page 265
Activity table
Page 383 · table single