Activity record

PGDB_A034055

Assay: viabilityTarget: GSPT1QC: manual_curated
Activity overview

IC50 = > 3-5 nM

TargetGSPT1
Cell lineMV-4-11
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002456
PatentCN120289428A
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000713
Compound IDPGDB_C000713
Compound实施例21
Source record IDPGDB_C000713
InChIKeyLTDUIDOAKBULQV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002456
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDCN120289428A
Compound location

实施例21

实施例21 enlarged structure实施例21 location on patent page 44
Activity table
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