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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A034365

Assay: cellular_functionTarget: BRD4QC: ambiguous

Activity overview

EC50 = 8.66 uM

TargetBRD4

E3 ligaseCRBN

Cell lineFlip-InTM293

Time5 h

Assay / Readoutflow_cytometry / EC50

Assay IDPGDB_AS001859

PatentUS12110292B2

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C009015

Compound31;31;31

Source record IDPGDB_C009015

InChIKeyZHPZHNGAVZNJLK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001859

Assay familycellular_function

Assay systemcell_based

ReadoutEC50

Technologyflow_cytometry

Treatment time5 h

TargetBRD4

E3CRBN

Cell lineFlip-InTM293

Organismmammalian

Source evidence

Patent IDUS12110292B2

Compound location

31;31;31

31;31;31 enlarged structure

31;31;31 location on patent page 30

Activity table

Page 102 · table start

Page 103 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU