Activity record

PGDB_A034707

Assay: viabilityTarget: BTKQC: standardized
Activity overview

IC50 = 100-500 nM

TargetBTK
Cell lineMV-4-11
Time72 h
Assay / ReadoutCCK-8 / viability
Assay IDPGDB_AS000080
PatentCN116239566A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025811
Compound IDPGDB_C025811
CompoundGT-02744
Source record IDPGDB_C015981
InChIKeyVGHSRMOLPXCWHF-MIJJZIGMSA-N

Assay context

Assay IDPGDB_AS000080
Assay familyviability
Assay systemcell_based
Readoutviability
TechnologyCCK-8
Treatment time72 h
Detection target% Cell viability
TargetBTK
E3Not specified
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDCN116239566A
Compound location

GT-02744

GT-02744 enlarged structureGT-02744 location on patent page 279
Activity table
Page 844 · table start
Page 845 · table end