Activity record

PGDB_A034915

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 2.78 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000788
PatentWO2023151635A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002024
Compound IDPGDB_C002024
CompoundGT-02645
Source record IDPGDB_C002024
InChIKeyRKROHFOPAOBOOC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000788
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2023151635A1
Compound location

GT-02645

GT-02645 enlarged structureGT-02645 location on patent page 278
Activity table
Page 358 · table single