Activity record

PGDB_A035062

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

DC50 = 10-100 nM

TargetIKZF1
Cell lineMV-4-11
Time16 h
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS000050
PatentCN121471230A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001053
Compound IDPGDB_C001053
Compound9;9;实施例9
Source record IDPGDB_C001053
InChIKeyNBQVFJYKPUHZLM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000050
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Treatment time16 h
Detection targetprotein_degradation
TargetIKZF1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDCN121471230A
Compound location

9;9;实施例9

9;9;实施例9 enlarged structure9;9;实施例9 location on patent page 5
Activity table
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