PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

16 activity records

Assay family% Degradation

Systemcell_based

ReadoutDC50

TargetIKZF1

E3Not specified

Cell lineMV-4-11

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

16 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
DC50	-	=	100-1000	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A014910	PGDB_C001060	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A015784	PGDB_C001058	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A027607	PGDB_C001062	PGDB_AS000050	View
DC50	-	=	100-1000	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A032595	PGDB_C001049	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A035062	PGDB_C001053	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A038568	PGDB_C001057	PGDB_AS000050	View
DC50	-	=	100-1000	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A041042	PGDB_C001063	PGDB_AS000050	View
DC50	-	=	100-1000	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A044983	PGDB_C001061	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A046206	PGDB_C001051	PGDB_AS000050	View
DC50	-	<	10	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A052049	PGDB_C001059	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A055694	PGDB_C001052	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A056442	PGDB_C001054	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A070497	PGDB_C001056	PGDB_AS000050	View
DC50	-	=	10-100	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A072295	PGDB_C001048	PGDB_AS000050	View
DC50	-	>	1000	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A073591	PGDB_C001050	PGDB_AS000050	View
DC50	-	=	100-1000	nM	-	—	IKZF1	-	MV-4-11	CN121471230A	PGDB_A075474	PGDB_C001046	PGDB_AS000050	View

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