Activity record

PGDB_A035209

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

IC50 = 56 nM

TargetIKZF3
Cell lineOPM-2
Time5 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001698
PatentAU2019272751B2
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009601
Compound IDPGDB_C009601
CompoundPomalidomide
Source record IDPGDB_C000056
InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001698
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time5 d
Detection targetcell_proliferation
TargetIKZF3
E3Not specified
Cell lineOPM-2

Source evidence

Patent IDAU2019272751B2
Activity table
Page 206 · table single