Activity record

PGDB_A035304

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 0.005 uM

TargetIKZF2
Cell lineHEK293T
Time24 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS002115
PatentCN117836288A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000388
Compound IDPGDB_C000388
Compound27;27;27
Source record IDPGDB_C000388
InChIKeyOPAYBHCYDYLUNS-PFIFLBKHSA-N

Assay context

Assay IDPGDB_AS002115
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDCN117836288A
Compound location

27;27;27

27;27;27 enlarged structure27;27;27 location on patent page 38
Activity table
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