Assay

PGDB_AS002115

System: cell_basedTarget: IKZF2Cell line: HEK293T
Assay context summary

Assay context

10 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF2
E3Not specified
Cell lineHEK293T
Technologyfluorescence
Detection targetprotein_degradation
Activity compounds and values

Activity records

10 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C000381
DC50-=0.006uM-—IKZF2-HEK293TCN117836288APGDB_A009549PGDB_C000381PGDB_AS002115View
2D structure for PGDB_C000385
DC50-=0.004uM-—IKZF2-HEK293TCN117836288APGDB_A015856PGDB_C000385PGDB_AS002115View
2D structure for PGDB_C000387
DC50-=0.005uM-—IKZF2-HEK293TCN117836288APGDB_A029959PGDB_C000387PGDB_AS002115View
2D structure for PGDB_C000388
DC50-=0.005uM-—IKZF2-HEK293TCN117836288APGDB_A035304PGDB_C000388PGDB_AS002115View
2D structure for PGDB_C000389
DC50-=0.0005uM-—IKZF2-HEK293TCN117836288APGDB_A037440PGDB_C000389PGDB_AS002115View
2D structure for PGDB_C000386
DC50-=0.004uM-—IKZF2-HEK293TCN117836288APGDB_A039097PGDB_C000386PGDB_AS002115View
2D structure for PGDB_C000382
DC50->30uM-—IKZF2-HEK293TCN117836288APGDB_A050538PGDB_C000382PGDB_AS002115View
2D structure for PGDB_C000383
DC50->30uM-—IKZF2-HEK293TCN117836288APGDB_A060804PGDB_C000383PGDB_AS002115View
2D structure for PGDB_C000384
DC50-=0.292uM-—IKZF2-HEK293TCN117836288APGDB_A064076PGDB_C000384PGDB_AS002115View
2D structure for PGDB_C000380
DC50-=0.024uM-—IKZF2-HEK293TCN117836288APGDB_A070516PGDB_C000380PGDB_AS002115View
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