Activity record

PGDB_A035330

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 20-30 %

TargetIKZF3
Cell lineA375
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001349
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024246
Compound IDPGDB_C024246
CompoundGT-10496
Source record IDPGDB_C024246
InChIKeyHUOGLRSBJAEHSN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001349
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineA375
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10496

GT-10496 enlarged structureGT-10496 location on patent page 34
Activity table
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