PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

57 activity records

Assay familyviability

Systemcell_based

Readout% Inhibition

E3Not specified

Cell lineA375

OrganismHomo sapiens

Detection target% Cell viability

Activity compounds and values

Activity records

57 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Inhibition	-	=	40-50	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A010255	PGDB_C024213	PGDB_AS001349	View
% Inhibition	-	=	40-50	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A010392	PGDB_C024197	PGDB_AS001349	View
% Inhibition	-	=	30-40	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A014669	PGDB_C024194	PGDB_AS001349	View
% Inhibition	-	=	70-80	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A018250	PGDB_C024230	PGDB_AS001349	View
% Inhibition	-	=	0-10	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A018537	PGDB_C024241	PGDB_AS001349	View
% Inhibition	-	=	50-60	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A019368	PGDB_C024233	PGDB_AS001349	View
% Inhibition	-	=	70-80	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A024166	PGDB_C024229	PGDB_AS001349	View
% Inhibition	-	=	10-20	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A024608	PGDB_C024210	PGDB_AS001349	View
% Inhibition	-	=	10-20	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A025083	PGDB_C024202	PGDB_AS001349	View
% Inhibition	-	=	50-60	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A025600	PGDB_C024200	PGDB_AS001349	View
% Inhibition	-	=	10-20	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A025877	PGDB_C024220	PGDB_AS001349	View
% Inhibition	-	=	50-60	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A026377	PGDB_C024235	PGDB_AS001349	View
% Inhibition	-	=	60-70	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A028578	PGDB_C024226	PGDB_AS001349	View
% Inhibition	-	=	20-30	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A028656	PGDB_C024242	PGDB_AS001349	View
% Inhibition	-	=	10-20	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A032857	PGDB_C024218	PGDB_AS001349	View
% Inhibition	-	=	30-40	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A032942	PGDB_C024206	PGDB_AS001349	View
% Inhibition	-	=	40-50	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A032948	PGDB_C024239	PGDB_AS001349	View
% Inhibition	-	=	30-40	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A034631	PGDB_C024244	PGDB_AS001349	View
% Inhibition	-	=	70-80	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A034863	PGDB_C024243	PGDB_AS001349	View
% Inhibition	-	=	20-30	%	10 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A035330	PGDB_C024246	PGDB_AS001349	View

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