Activity record

PGDB_A035464

Assay: biochemicalTarget: CRBNQC: ambiguous
Activity overview

DC50 = 11 nM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000325
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020438
Compound IDPGDB_C020438
Compound268
Source record IDPGDB_C016568
InChIKeyVXGVZKIPKINMDI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000325
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

268

268 enlarged structure268 location on patent page 87
Activity table
Page 416 · table single