Assay

PGDB_AS000325

System: biochemicalTarget: CRBN
Assay context summary

Assay context

19 activity records
Assay familybiochemical
Systembiochemical
ReadoutEC50
TargetCRBN
E3CRBN
TechnologyHTRF
Activity compounds and values

Activity records

19 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C020442
DC50-=1nM-—CRBNCRBN-WO2025024521A1PGDB_A007157PGDB_C020442PGDB_AS000325View
2D structure for PGDB_C020447
DC50-=1000nM-—CRBNCRBN-WO2025024521A1PGDB_A009379PGDB_C020447PGDB_AS000325View
2D structure for PGDB_C020435
DC50-=12nM-—CRBNCRBN-WO2025024521A1PGDB_A020679PGDB_C020435PGDB_AS000325View
2D structure for PGDB_C020452
DC50-=672nM-—CRBNCRBN-WO2025024521A1PGDB_A030669PGDB_C020452PGDB_AS000325View
2D structure for PGDB_C020438
DC50-=11nM-—CRBNCRBN-WO2025024521A1PGDB_A035464PGDB_C020438PGDB_AS000325View
2D structure for PGDB_C020439
DC50-=15nM-—CRBNCRBN-WO2025024521A1PGDB_A037256PGDB_C020439PGDB_AS000325View
2D structure for PGDB_C020454
DC50-=179nM-—CRBNCRBN-WO2025024521A1PGDB_A042076PGDB_C020454PGDB_AS000325View
2D structure for PGDB_C020448
DC50-=190nM-—CRBNCRBN-WO2025024521A1PGDB_A044467PGDB_C020448PGDB_AS000325View
2D structure for PGDB_C020445
DC50-=312nM-—CRBNCRBN-WO2025024521A1PGDB_A046515PGDB_C020445PGDB_AS000325View
2D structure for PGDB_C020455
DC50-=26nM-—CRBNCRBN-WO2025024521A1PGDB_A049494PGDB_C020455PGDB_AS000325View
2D structure for PGDB_C020440
DC50-=3nM-—CRBNCRBN-WO2025024521A1PGDB_A052704PGDB_C020440PGDB_AS000325View
2D structure for PGDB_C020436
DC50-=7nM-—CRBNCRBN-WO2025024521A1PGDB_A055502PGDB_C020436PGDB_AS000325View
2D structure for PGDB_C020446
DC50-=136nM-—CRBNCRBN-WO2025024521A1PGDB_A059468PGDB_C020446PGDB_AS000325View
2D structure for PGDB_C020450
DC50-=155nM-—CRBNCRBN-WO2025024521A1PGDB_A066291PGDB_C020450PGDB_AS000325View
2D structure for PGDB_C020451
DC50-=76nM-—CRBNCRBN-WO2025024521A1PGDB_A071755PGDB_C020451PGDB_AS000325View
2D structure for PGDB_C020453
DC50-=143nM-—CRBNCRBN-WO2025024521A1PGDB_A072055PGDB_C020453PGDB_AS000325View
2D structure for PGDB_C020444
DC50-=213nM-—CRBNCRBN-WO2025024521A1PGDB_A072512PGDB_C020444PGDB_AS000325View
2D structure for PGDB_C020437
DC50-=100nM-—CRBNCRBN-WO2025024521A1PGDB_A075532PGDB_C020437PGDB_AS000325View
2D structure for PGDB_C020449
DC50-=33nM-—CRBNCRBN-WO2025024521A1PGDB_A077808PGDB_C020449PGDB_AS000325View
Page 1 of 1 · 19 records