Activity record

PGDB_A035540

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

GI50 = 100-1000 nM

TargetGSPT1
Cell lineHL-60
Time48 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS001555
PatentWO2023237116A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002285
Compound IDPGDB_C002285
CompoundExample 105
Source record IDPGDB_C002285
InChIKeyPTIFAJRIJJKNRS-FKCXMHPPSA-N

Assay context

Assay IDPGDB_AS001555
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023237116A1
Compound location

Example 105

Example 105 enlarged structureExample 105 location on patent page 319
Activity table
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