Activity record

PGDB_A035715

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.013 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000522
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008050
Compound IDPGDB_C008050
Compound120;120;120
Source record IDPGDB_C008050
InChIKeyQYOYGKLCFLMELJ-BYICEURKSA-N

Assay context

Assay IDPGDB_AS000522
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

120;120;120

120;120;120 enlarged structure120;120;120 location on patent page 41
Activity table
Page 529 · table start
Page 530 · table middle
Page 531 · table middle
Page 532 · table end