Activity record

PGDB_A035775

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 100.36 %

TargetGSPT1
Cell lineHEK293T
Time18 h
Assay / Readoutluminescence / % Degradation
Assay IDPGDB_AS000448
PatentWO2023001028A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001866
Compound IDPGDB_C001866
CompoundWX013;WX013
Source record IDPGDB_C001866
InChIKeyLYRHHLFPSKBMOC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000448
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyluminescence
Treatment time18 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDWO2023001028A1
Compound location

WX013;WX013

WX013;WX013 enlarged structureWX013;WX013 location on patent page 38
Activity table
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