Activity record

PGDB_A035818

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 0.46 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000788
PatentWO2023151635A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001163
Compound IDPGDB_C001163
CompoundGT-02494
Source record IDPGDB_C001163
InChIKeyQIVBYMZVLRKNGX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000788
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2023151635A1
Compound location

GT-02494

GT-02494 enlarged structureGT-02494 location on patent page 266
Activity table
Page 358 · table single