Activity record

PGDB_A036375

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 5.2 nM

TargetIKZF2
Time20 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS002052
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009144
Compound IDPGDB_C009144
CompoundEXAMPLE 1
Source record IDPGDB_C009144
InChIKeyPKEKMIKJWMHBLO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002052
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time20 h
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDUS20250129061A1
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 69
Activity table
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