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SIMM · NJU
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SIMM · NJU
Activity record
PGDB_A036694
Assay: % Degradation
Target: IKZF1
QC: ambiguous
Activity overview
degradation <= 25 %
Target
IKZF1
E3 ligase
CRBN
Cell line
NCI-H929
Concentration
20 uM
Time
24 h
Assay / Readout
Western_blot / % Degradation
Assay ID
PGDB_AS000227
Patent
AU2020392427A1
QC status
ambiguous
Evidence details
Compound, assay context, and source
Compound
Compound ID
PGDB_C019025
Compound
1;1;1
Source record ID
PGDB_C019013
InChIKey
UCBICYVSLYTGCN-UHFFFAOYSA-N
Assay context
Assay ID
PGDB_AS000227
Assay family
% Degradation
Assay system
cell_based
Readout
% Degradation
Technology
Western_blot
Concentration
20 uM
Treatment time
24 h
Detection target
protein_degradation
Target
IKZF1
E3
CRBN
Cell line
NCI-H929
Organism
Homo sapiens
Source evidence
Patent ID
AU2020392427A1
Compound location
1;1;1
Activity table