Assay

PGDB_AS000227

System: cell_basedTarget: IKZF1Cell line: NCI-H929
Assay context summary

Assay context

9 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetIKZF1
E3CRBN
Cell lineNCI-H929
OrganismHomo sapiens
TechnologyWestern_blot
Detection targetprotein_degradation
Activity compounds and values

Activity records

9 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C019016
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A011398PGDB_C019016PGDB_AS000227View
2D structure for PGDB_C019027
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A018685PGDB_C019027PGDB_AS000227View
2D structure for PGDB_C019017
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A026772PGDB_C019017PGDB_AS000227View
2D structure for PGDB_C019020
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A036477PGDB_C019020PGDB_AS000227View
2D structure for PGDB_C019025
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A036694PGDB_C019025PGDB_AS000227View
2D structure for PGDB_C019029
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A050994PGDB_C019029PGDB_AS000227View
2D structure for PGDB_C019040
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A052452PGDB_C019040PGDB_AS000227View
2D structure for PGDB_C019028
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A055161PGDB_C019028PGDB_AS000227View
2D structure for PGDB_C019014
% Degradation-<=25%20 uM24 hIKZF1CRBNNCI-H929AU2020392427A1PGDB_A068974PGDB_C019014PGDB_AS000227View
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