Activity record

PGDB_A037631

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

DC50 = 1076 nM

TargetIKZF1
Cell lineJurkat
Time72 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS002138
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009144
Compound IDPGDB_C009144
CompoundEXAMPLE 1
Source record IDPGDB_C009144
InChIKeyPKEKMIKJWMHBLO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002138
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time72 h
TargetIKZF1
E3Not specified
Cell lineJurkat

Source evidence

Patent IDUS20250129061A1
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 69
Activity table
Page 79 · table single