Activity record

PGDB_A037664

Assay: biochemicalTarget: CRBNQC: ambiguous
Activity overview

inhibition = 60-80 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Time3 h
Assay / ReadoutHTRF / Kd
Assay IDPGDB_AS001510
PatentWO2024245444A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C023631
Compound IDPGDB_C023631
CompoundGT-08087
Source record IDPGDB_C014204
InChIKeyBLPILYYHMOMHAD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001510
Assay familybiochemical
Assay systemcell_based
ReadoutKd
TechnologyHTRF
Concentration2 uM
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024245444A1
Compound location

GT-08087

GT-08087 enlarged structureGT-08087 location on patent page 78
Activity table
Page 260 · table single