PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

9 activity records

Assay familybiochemical

Systemcell_based

ReadoutKd

TargetCRBN

E3CRBN

OrganismHomo sapiens

TechnologyHTRF

Activity compounds and values

Activity records

9 records

Structure	Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
	% Inhibition	-	=	53-60	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A007589	PGDB_C023633	PGDB_AS001510	View
	% Inhibition	-	=	60-80	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A020078	PGDB_C014201	PGDB_AS001510	View
	% Inhibition	-	=	53-60	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A020430	PGDB_C014202	PGDB_AS001510	View
	% Inhibition	-	=	60-80	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A037664	PGDB_C023631	PGDB_AS001510	View
	% Inhibition	-	=	60-80	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A055145	PGDB_C023634	PGDB_AS001510	View
	% Inhibition	-	=	60-80	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A067131	PGDB_C014200	PGDB_AS001510	View
	% Inhibition	-	=	53-60	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A070054	PGDB_C014203	PGDB_AS001510	View
	% Inhibition	-	=	53-60	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A074273	PGDB_C023635	PGDB_AS001510	View
	% Inhibition	-	=	53-60	%	2 uM	3 h	CRBN	CRBN	-	WO2024245444A1	PGDB_A074470	PGDB_C023632	PGDB_AS001510	View

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