Activity record

PGDB_A038248

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 11.8 nM

TargetGSPT1
Cell lineU937
Time6 h
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS002566
PatentCN117917402A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000497
Compound IDPGDB_C000497
CompoundWYY-27
Source record IDPGDB_C000531
InChIKeyMFPOLQFZNNMBQF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002566
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineU937

Source evidence

Patent IDCN117917402A
Activity table
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