PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN117917402A

AssigneeJinan University, Livzon Pharmaceutical Group

TitleIsoindoleamide compounds and pharmaceutical compositions and applications thereof

Family ID90730012

Family members1

Filing year2023

Publication date2024-04-23

JurisdictionCN

Compounds34

Activity records166

Assays5

Activity compounds and values

Activity records

166 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	=	702.1	nM	-	—	GSPT1	-	U937	PGDB_A007093	PGDB_C000498	PGDB_AS002566	View
IC50	-	=	3.511	nM	-	—	GSPT1	-	MV-4-11	PGDB_A007276	PGDB_C000492	PGDB_AS000703	View
IC50	-	=	8720	nM	-	—	GSPT1	-	H1299	PGDB_A007432	PGDB_C000485	PGDB_AS002493	View
IC50	-	>	10000	nM	-	—	GSPT1	-	U937	PGDB_A008444	PGDB_C000501	PGDB_AS002565	View
DC50	-	=	86.4	nM	-	—	GSPT1	-	U937	PGDB_A009268	PGDB_C000487	PGDB_AS002566	View
IC50	-	=	1150	nM	-	—	GSPT1	-	MV-4-11	PGDB_A009326	PGDB_C000478	PGDB_AS000703	View
IC50	-	=	291.9	nM	-	—	GSPT1	-	U937	PGDB_A010847	PGDB_C000494	PGDB_AS002565	View
IC50	-	>	10000	nM	-	—	GSPT1	-	MV-4-11	PGDB_A011392	PGDB_C000481	PGDB_AS000703	View
IC50	-	=	570	nM	-	—	GSPT1	-	H1299	PGDB_A011495	PGDB_C000486	PGDB_AS002493	View
IC50	-	=	57.43	nM	-	—	-	-	MOLT-4	PGDB_A012013	PGDB_C000492	PGDB_AS002289	View
IC50	-	>	10000	nM	-	—	-	-	MOLT-4	PGDB_A012241	PGDB_C000504	PGDB_AS002289	View
DC50	-	=	283.4	nM	-	—	GSPT1	-	U937	PGDB_A012736	PGDB_C000494	PGDB_AS002566	View
IC50	-	=	222.8	nM	-	—	GSPT1	-	MV-4-11	PGDB_A013245	PGDB_C000477	PGDB_AS000703	View
IC50	-	=	18.25	nM	-	—	GSPT1	-	MV-4-11	PGDB_A013358	PGDB_C000495	PGDB_AS000703	View
IC50	-	=	9.611	nM	-	—	GSPT1	-	MV-4-11	PGDB_A013454	PGDB_C000496	PGDB_AS000703	View
IC50	-	=	6752	nM	-	—	GSPT1	-	H1299	PGDB_A013472	PGDB_C000502	PGDB_AS002493	View
DC50	-	>	10000	nM	-	—	GSPT1	-	U937	PGDB_A013841	PGDB_C000476	PGDB_AS002566	View
IC50	-	>	10000	nM	-	—	-	-	MOLT-4	PGDB_A014122	PGDB_C000476	PGDB_AS002289	View
IC50	-	=	120.3	nM	-	—	GSPT1	-	MV-4-11	PGDB_A014965	PGDB_C000473	PGDB_AS000703	View
IC50	-	=	31.37	nM	-	—	GSPT1	-	U937	PGDB_A015083	PGDB_C000474	PGDB_AS002565	View

Rows per pagePage 1 of 9 · 166 recordsGo to page