Activity record

PGDB_A038266

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 65.68 nM

TargetCRBN
E3 ligaseCRBN
Time15 min
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000570
PatentCN118852145A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001457
Compound IDPGDB_C001457
Compound实施例5
Source record IDPGDB_C001457
InChIKeyJHKRXHGJFSVZQU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000570
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time15 min
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN118852145A
Compound location

实施例5

实施例5 enlarged structure实施例5 location on patent page 31
Activity table
Page 91 · table start
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