Activity record

PGDB_A039143

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 18 nM

TargetIKZF2
Time13 d
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001515
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010131
Compound IDPGDB_C010131
Compound2
Source record IDPGDB_C010131
InChIKeySTBPHXSTASSXPE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001515
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time13 d
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

2

2 enlarged structure2 location on patent page 78
Activity table
Page 93 · table single