Activity record

PGDB_A039175

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 = 83 nM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS000407
PatentWO2024125437A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005360
Compound IDPGDB_C005360
Compound实施例 1
Source record IDPGDB_C005360
InChIKeyTWEABVLRPZMDKD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000407
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2024125437A1
Compound location

实施例 1

实施例 1 enlarged structure实施例 1 location on patent page 13
Activity table
Page 37 · table single