Activity record

PGDB_A039645

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 1.3 nM

TargetGSPT1
Cell lineNCI-H69
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001964
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001866
Compound IDPGDB_C001866
CompoundWX013;WX013
Source record IDPGDB_C001866
InChIKeyLYRHHLFPSKBMOC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001964
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H69

Source evidence

Patent IDWO2023001028A1
Compound location

WX013;WX013

WX013;WX013 enlarged structureWX013;WX013 location on patent page 38
Activity table
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